Dosage: Oral

For: Hypertension

Adult: Initially, 40 mg once daily, may be adjusted to 20-80 mg once daily according to clinical response. Max: 80 mg once daily.

Renal impairment: Severe or on haemodialysis: Initially, 20 mg once daily.

Hepatic impairment: Mild to moderate: Max: 40 mg once daily. Severe: Contraindicated.

For: Cardiovascular risk reduction

Adult: 80 mg once daily.

Renal impairment: Severe or on haemodialysis: Initially, 20 mg once daily.

Hepatic impairment: Mild to moderate: Max: 40 mg once daily. Severe: Contraindicated.